Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Houghton, R.L.; Fisher, R.R.; Sanadi, D.R.
    Dependence of Escherichia coli pyridine nucleotide transhydrogenase on phospholipids and its sensitivity (1976), Biochem. Biophys. Res. Commun., 73, 751-757.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.6.1.2 asolectin 10fold stimulation of partially purified enzyme Escherichia coli
1.6.1.2 cardiolipin 10fold stimulation of partially purified enzyme with Escherichia coli cardiolipin Escherichia coli
1.6.1.2 lecithin 5fold stimulation of partially purified enzyme Escherichia coli
1.6.1.2 Phospholipids approx. 15fold stimulation of partially purified enzyme with crude Escherichia coli lipid fraction Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.1.2 glutathione protection by NADP+ or NAD+, presence of NADPH accelerates inhibition Escherichia coli
1.6.1.2 methylmethane thiosulfonate 10 mM, approx. 80% inactivation after 320 min, approx. 40% in the presence of NADP+ or NAD+, approx. 90% in the presence of NADPH Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.6.1.2 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.6.1.2 partially purified Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.6.1.2 13.6
-
 partially purified enzyme, assay in the presence of Escherichia coli phospholipids Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.1.2 NAD+
-
 Escherichia coli
1.6.1.2 NADH
-
 Escherichia coli
1.6.1.2 NADP+
-
 Escherichia coli
1.6.1.2 NADPH
-
 Escherichia coli