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Literature summary extracted from

  • Phelps, D.C.; Hatefi, Y.
    Inhibition of the mitochondrial nicotinamide nucleotide transhydrogenase by dicyclohexylcarbodiimide and diethylpyrocarbonate (1981), J. Biol. Chem., 256, 8217-8221.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.1.2 diethyldicarbonate inhibition is approx. 50% accelerated in the presence of NAD(H) Bos taurus
1.6.1.2 N,N'-Dicylclohexylcarbodiimide maximal inhibition at pH 6.5, NAD(H) and oxidized or reduced acetylpyridine adenine dinucleotide completely protect from inactivation, NADP+ increases the inhibition rate Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.1.2 mitochondrial membrane
-
 Bos taurus 31966
-

Organism

EC Number Organism UniProt Comment Textmining
1.6.1.2 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.6.1.2 heart
-
 Bos taurus
-

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.1.2 NAD+
-
 Bos taurus
1.6.1.2 NADH
-
 Bos taurus
1.6.1.2 NADP+
-
 Bos taurus
1.6.1.2 NADPH
-
 Bos taurus