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Literature summary extracted from
- Purification and properties of dihydrofolate reductase from cultured mammalian cells (1973), Biochem. J., 133, 349-356.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.1.3 | KCl | - |
Homo sapiens |  |
| 1.5.1.3 | p-hydroxymercuribenzoate | - |
Homo sapiens | |
| 1.5.1.3 | Urea | - |
Homo sapiens | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.1.3 | methotrexate | - |
Homo sapiens | |
| 1.5.1.3 | trimethoprim | - |
Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.1.3 | K+ | stimulation | Homo sapiens | |
| 1.5.1.3 | organic mercurials | cultured mammalian cells: activation | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.5.1.3 | Homo sapiens | - |
cultured mammalian cells, overview | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 1.5.1.3 | cultured mammalian cells, overview | Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.5.1.3 | HeLa cell | - |
Homo sapiens | - |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.5.1.3 | NADPH | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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