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Literature summary extracted from

  • Frebort, I.; Tamaki, H.; Ishida, H.; Pec, P.; Luhova, L.; Tsuno, H.; Halata, M.; Asano, Y.; Kato, Y.; et al.
    Two distinct quinoprotein amine oxidases are induced by n-butylamine in the mycelia of Aspergillus niger AKU 3302. Purification, characterization, cDNA cloning and sequencing (1996), Eur. J. Biochem., 237, 255-265.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.22 (E)-1,4-diamino-2-butene 0.1 mM, 72% and 87% inhibition; 0.1 mM, 72% and 87% inhibition Aspergillus niger
1.4.3.22 (Z)-1,4-diamino-2-butene 0.1 mM, 28% inhibition; 0.1 mM, 28% inhibition Aspergillus niger
1.4.3.22 1,4-phenanthroline
-
 Aspergillus niger
1.4.3.22 1,5-Diamino-3-pentanone 1 mM, 50% inhibition; 1 mM, 50% inhibition Aspergillus niger
1.4.3.22 1-amino-3-phenyl-3-propanone
-
 Aspergillus niger
1.4.3.22 2,2'-dipyridyl
-
 Aspergillus niger
1.4.3.22 2,4-Dinitrophenylhydrazine 1 mM, complete inhibition; 1 mM, complete inhibition Aspergillus niger
1.4.3.22 p-Nitrophenylhydrazine 1 mM, complete inhibition; 1 mM, complete inhibition Aspergillus niger
1.4.3.22 phenylhydrazine 1 mM, complete inhibition; 1 mM, complete inhibition Aspergillus niger
1.4.3.22 Quinacrine 0.1 mM, 73% inhibition; 67% inhibition Aspergillus niger
1.4.3.22 sanguinarine 0.1 mM, 65% inhibition; 0.1 mM, 65% inhibition Aspergillus niger

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.22 0.15
-
 aminohexane
-
 Aspergillus niger

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.22 copper 0.09-0.2 copper atoms per subunit Aspergillus niger
1.4.3.22 copper 0.5 copper atoms per subunit Aspergillus niger

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.22 75000
-
 2 * 75000, SDS-PAGE, deduced from nucleotide sequence Aspergillus niger
1.4.3.22 80000
-
 gel filtration Aspergillus niger
1.4.3.22 150000
-
 gel filtration Aspergillus niger

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Aspergillus niger
-
-
-
1.4.3.22 Aspergillus niger Q12556
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.4.3.22 glycoprotein less than 0.8% Aspergillus niger
1.4.3.22 glycoprotein less than 0.3% Aspergillus niger

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.22
-
 Aspergillus niger

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.22 mycelium
-
 Aspergillus niger
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.22 0.72
-
 aminoheptane Aspergillus niger
1.4.3.22 1.74
-
 aminoheptane Aspergillus niger
1.4.3.22 2.76
-
 benzylamine Aspergillus niger
1.4.3.22 7.68
-
 aminoheptane Aspergillus niger

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 (E,Z)-1,4-diamino-2-butene + H2O + O2
-
 Aspergillus niger 4-aminobut-2-enal + NH3 + H2O2
-
 ?
1.4.3.22 1,4-diaminobutane + H2O + O2
-
 Aspergillus niger 4-aminobutanal + NH3 + H2O2
-
 ?
1.4.3.22 1,5-diaminopentane + H2O + O2
-
 Aspergillus niger 5-aminopentanal + NH3 + H2O2
-
 ?
1.4.3.22 aminobutane + H2O + O2
-
 Aspergillus niger butanal + NH3 + H2O2
-
 ?
1.4.3.22 aminohexane + H2O + O2
-
 Aspergillus niger hexanal + NH3 + H2O2
-
 ?
1.4.3.22 benzylamine + H2O + O2
-
 Aspergillus niger benzaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 histamine + H2O + O2
-
 Aspergillus niger (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 p-dimethylaminomethylbenzylamine + H2O + O2
-
 Aspergillus niger p-dimethylaminomethylbenzaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 RCH2NH2 + H2O + O2
-
 Aspergillus niger RCHO + NH3 + H2O2
-
 ?
1.4.3.22 tyramine + H2O + O2
-
 Aspergillus niger 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.22 dimer 2 * 75000, SDS-PAGE, deduced from nucleotide sequence Aspergillus niger
1.4.3.22 monomer 1 * 80000, SDS-PAGE Aspergillus niger

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.22 7.5
-
-
 Aspergillus niger

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.22 2,4,5-trihydroxyphenylalanine quinone
-
 Aspergillus niger