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Literature summary extracted from

  • Costa, M.T.; Rotilio, G.; Agro, A.F.; Vallogini, M.P.; Mondovi, B.
    On the active site of diamine oxidase: kinetic studies (1971), Arch. Biochem. Biophys., 147, 8-13.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.22 m-phenylenediamine competitive vs. cadaverine Sus scrofa
1.4.3.22 additional information no substrate inhibition with monoamines; substrate inhibition with diamines Sus scrofa
1.4.3.22 o-phenyldiamine
-
 Sus scrofa
1.4.3.22 o-phenylenediamine competitive vs. cadaverine Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.22 0.065
-
 histamine at pH 7.4 Sus scrofa
1.4.3.22 0.083
-
 histamine at pH 6.3 Sus scrofa
1.4.3.22 0.17
-
 histamine at pH 8.5 Sus scrofa
1.4.3.22 0.73
-
 cadaverine at pH 7.4 Sus scrofa
1.4.3.22 0.83
-
 cadaverine at pH 8.5 Sus scrofa
1.4.3.22 1.3
-
 cadaverine at pH 6.3 Sus scrofa
1.4.3.22 3
-
 Butylamine at pH 8.5 Sus scrofa
1.4.3.22 4
-
 Butylamine at pH 6.3 Sus scrofa
1.4.3.22 5
-
 Butylamine at pH 7.4 Sus scrofa
1.4.3.22 6.5
-
 lysine methylester at pH 7.4 Sus scrofa
1.4.3.22 6.6
-
 Propylamine at pH 7.4 Sus scrofa
1.4.3.22 66
-
 ethylamine at pH 7.4 Sus scrofa
1.4.3.22 66
-
 ethylenediamine at pH 7.4 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.22 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.22 kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.22 butylamine + H2O + O2
-
 Sus scrofa butanal + NH3 + H2O2
-
 r
1.4.3.22 ethylamine + H2O + O2
-
 Sus scrofa acetaldehyde + NH3 + H2O2
-
 r
1.4.3.22 ethylenediamine + H2O + O2
-
 Sus scrofa ?
-
 r
1.4.3.22 histamine + H2O + O2
-
 Sus scrofa (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.22 L-lysine methyl ester + H2O + O2
-
 Sus scrofa ?
-
 ?
1.4.3.22 propylamine + H2O + O2
-
 Sus scrofa propanal + NH3 + H2O2
-
 r
1.4.3.22 RCH2NH2 + H2O + O2
-
 Sus scrofa RCHO + NH3 + H2O2
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.22 10
-
 o-phenyldiamine
-
 Sus scrofa
1.4.3.22 10
-
 m-phenyldiamine
-
 Sus scrofa