Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Churchich, J.E.
    Brain pyridoxine-5-phosphate oxidase. A dimeric enzyme containing one FMN site (1984), Eur. J. Biochem., 138, 327-332.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.5 pyridoxal 5'-phosphate
-
 Sus scrofa
1.4.3.5 pyridoxaloxime 5'-phosphate competitive inhibition Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.4.3.5 0.01
-
 5'-phospho-pyridoxyl-aniline
-
 Sus scrofa
1.4.3.5 0.01
-
 5'-phospho-pyridoxyl-3-aminobenzoate
-
 Sus scrofa
1.4.3.5 0.01
-
 5'-phospho-pyridoxyl-4-aminobenzoate
-
 Sus scrofa
1.4.3.5 0.013
-
 pyridoxine 5'-phosphate
-
 Sus scrofa
1.4.3.5 0.03
-
 pyridoxine 5'-phosphate
-
 Sus scrofa
1.4.3.5 0.03
-
 5'-phospho-pyridoxyl-4-aminobutyrate
-
 Sus scrofa
1.4.3.5 0.035
-
 5'-phospho-pyridoxyl-3-L-alanine
-
 Sus scrofa
1.4.3.5 0.1
-
 pyridoxamine-5'-phosphate
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.5 30000
-
 2 * 30000, drastic denaturation conditions: 0.1% SDS and 2-mercaptoethanol, SDS-PAGE Sus scrofa
1.4.3.5 60000
-
 polyacrylamide gradient gel electrophoresis Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.5 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.5
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.5 brain
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.5 0.09
-
-
 Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.5 5'-phospho-pyridoxyl-3-alanine + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + alanine + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-3-aminobenzoate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 3-aminobenzoate + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-3-L-alanine + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + L-alanine + H2O2
-
 r
1.4.3.5 5'-phospho-pyridoxyl-4-aminobenzoate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 4-aminobenzoate + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-4-aminobutyrate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 4-aminobutyrate + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-4-aminonitrobenzene + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 4-aminonitrobenzene + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-4-aminophenol + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 4-aminophenol + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-5-aminovalerate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + 5-aminovalerate + H2O2
-
 ?
1.4.3.5 5'-phospho-pyridoxyl-aniline + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + aniline + H2O2
-
 ?
1.4.3.5 pyridoxamine 5'-phosphate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + NH3 + H2O2
-
 ?
1.4.3.5 pyridoxine 5'-phosphate + H2O + O2
-
 Sus scrofa pyridoxal 5'-phosphate + H2O2
-
 ?

Subunits

EC Number Subunits Comment Organism
1.4.3.5 dimer 2 * 30000, drastic denaturation conditions: 0.1% SDS and 2-mercaptoethanol, SDS-PAGE Sus scrofa

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.4.3.5 0.004
-
 5'-phospho-pyridoxyl-p-aminophenol
-
 Sus scrofa
1.4.3.5 0.009
-
 pyridoxamine 5'-phosphate
-
 Sus scrofa
1.4.3.5 0.01
-
 5'-phospho-pyridoxyl-aniline
-
 Sus scrofa
1.4.3.5 0.035
-
 5'-phospho-pyridoxyl-5-aminovalerate
-
 Sus scrofa
1.4.3.5 0.04
-
 5'-phospho-pyridoxyl-3-alanine
-
 Sus scrofa
1.4.3.5 0.04
-
 5'-phospho-pyridoxyl-4-aminobutyrate
-
 Sus scrofa
1.4.3.5 0.09
-
 pyridoxine 5'-phosphate
-
 Sus scrofa
1.4.3.5 0.1
-
 5'-phospho-pyridoxyl-3-aminobenzoate
-
 Sus scrofa
1.4.3.5 0.1
-
 5'-phospho-pyridoxyl-p-aminonitrobenzene
-
 Sus scrofa

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.3.5 FMN flavoprotein Sus scrofa
1.4.3.5 FMN binds 1 mol of FMN per mol of dimer Sus scrofa