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Literature summary extracted from

  • Dadak, V.; Mala, G.; Kucera, I.
    Kinetic characterization of succinate dehydrogenase (succinate: ubiquinone oxidoreductase) from Paracoccus denitrificans (1988), Biologia (Bratisl. ), 43, 1077-1085.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.5.1 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole slightly activates Paracoccus denitrificans
1.3.5.1 antimycin A activates Paracoccus denitrificans
1.3.5.1 KCN activation at 6.7 mM up to 10 mM when both alternative pathways to oxygen are inhibited Paracoccus denitrificans
1.3.5.1 malonate activation Paracoccus denitrificans
1.3.5.1 Mucidin activates Paracoccus denitrificans
1.3.5.1 succinate activation Paracoccus denitrificans

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.5.1 5-(n-Undecyl)-6-hydroxy-4,7-oxobenzothiazole UHDBT Paracoccus denitrificans
1.3.5.1 CN- not inhibitory: when mixed with succinate or alone Paracoccus denitrificans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.5.1 0.27
-
 succinate for both membrane fragments and mitochondrial enzyme Paracoccus denitrificans

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.5.1 membrane
-
 Paracoccus denitrificans 16020
-
1.3.5.1 mitochondrion
-
 Paracoccus denitrificans 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.5.1 Paracoccus denitrificans
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.5.1 0.01
-
 measured by the rate of dichloroindophenol reduction Paracoccus denitrificans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.5.1 succinate + ubiquinone
-
 Paracoccus denitrificans fumarate + ubiquinol
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.5.1 7 7.2 phosphate buffer Paracoccus denitrificans
1.3.5.1 7.3
-
 Tris-acetate buffer Paracoccus denitrificans

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.3.5.1 6 7.5 slow decline of activity at acidic pH, fast decline in alkaline range Paracoccus denitrificans

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.3.5.1 7.5
-
 enzyme activity falls abruptly Paracoccus denitrificans