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Literature summary extracted from

  • Chu, C.; Mao, L.F.; Schulz, H.
    Estimation of peroxisomal.beta-oxidation in rat heart by a direct assay of acyl-CoA oxidase (1994), Biochem. J., 302, 23-29.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.3.6 2-bromopalmitic acid
-
 Rattus norvegicus
1.3.3.6 2-bromopalmitoyl-CoA
-
 Rattus norvegicus
1.3.3.6 2-tetradecylglycidic acid
-
 Rattus norvegicus
1.3.3.6 antimycin A with addition of rotenone Rattus norvegicus
1.3.3.6 Detergents no inhibition with Triton-X 100 Rattus norvegicus
1.3.3.6 KCN
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.3.6 peroxisome
-
 Rattus norvegicus 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.3.6 acyl-CoA + O2 Rattus norvegicus involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively trans-2,3-dehydroacyl-CoA + H2O2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.3.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.3.6 brain low content Rattus norvegicus
-
1.3.3.6 heart
-
 Rattus norvegicus
-
1.3.3.6 kidney
-
 Rattus norvegicus
-
1.3.3.6 liver
-
 Rattus norvegicus
-
1.3.3.6 skeletal muscle low content Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3.3.6 0.0006
-
 liver homogenate Rattus norvegicus
1.3.3.6 2.12
-
 purified enzyme Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.3.6 acyl-CoA + O2
-
 Rattus norvegicus trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
1.3.3.6 acyl-CoA + O2 involved in beta-oxidation of fatty acids in peroxisomes and glyoxysomes, respectively Rattus norvegicus trans-2,3-dehydroacyl-CoA + H2O2
-
 ?
1.3.3.6 dec-4-cis-enoyl-CoA + O2
-
 Rattus norvegicus 2-trans-4-cis-decadienoyl-CoA + H2O2
-
 ?
1.3.3.6 dec-4-trans-enoyl-CoA + O2
-
 Rattus norvegicus 2-trans-4-trans-decadienoyl-CoA + H2O2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.3.3.6 25
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.3.6 FAD
-
 Rattus norvegicus