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Literature summary extracted from

  • Mizugaki, M.; Nishimaki, T.; Yamamoto, H.; Nishimura, S.; Sagi, M.; Yamanaka, H.
    Studies on the metabolism of unsaturated fatty acids. VIII. Induction of 2,4-dienoyl-CoA reductase in Escherichia coli on the addition of unsaturated fatty acids (1982), J. Biochem., 91, 1453-1456.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.34 iodoacetic acid inhibition of 70-80% at concentration of 1 mM Escherichia coli
1.3.1.34 N-ethylmaleimide inhibition of 70-80% at concentration of 1 mM Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.34 Escherichia coli
-
-
-
1.3.1.34 Escherichia coli B / ATCC 11303
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.34 gel filtration Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.34 2-trans,4-trans-hexadienoyl-CoA + NADPH
-
 Escherichia coli ?
-
 ir
1.3.1.34 2-trans,4-trans-hexadienoyl-CoA + NADPH
-
 Escherichia coli B / ATCC 11303 ?
-
 ir

Synonyms

EC Number Synonyms Comment Organism
1.3.1.34 2,4-dienoyl-CoA reductase
-
 Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.1.34 7.4
-
 trans,trans-2,4-hexadienoyl-CoA + NADPH Escherichia coli

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.3.1.34 6 7.5 stable at 40°C for 10 min Escherichia coli
1.3.1.34 8
-
 activity loss about 50% Escherichia coli
1.3.1.34 9
-
 total loss of activity Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.34 NADPH not NADH Escherichia coli