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Literature summary extracted from
- Specific stimulation of steroid 5alpha-reductase solubilized from rat liver microsomes by endogenous phosphatidylserine (1987), Biochem. Biophys. Res. Commun., 149, 482-487.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.1.22 | dilauroylphosphatidylcholine | marked stimulatory effect on activity | Rattus norvegicus |  |
| 1.3.1.22 | phosphatidylserine | 4fold increase in activity | Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.3.1.22 | microsome | - |
Rattus norvegicus | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.3.1.22 | Rattus norvegicus | - |
female rat | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.3.1.22 | liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.3.1.22 | progesterone + NADPH + H+ | - |
Rattus norvegicus | 5alpha-pregnan-3-20-dione + NADP+ | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.3.1.22 | NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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