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Literature summary extracted from

  • Hyman, M.R.; Ensign, S.A.; Arp, D.J.; Ludden, P.W.
    Carbonyl sulfide inhibition of CO dehydrogenase from Rhodospirillum rubrum (1989), Biochemistry, 28, 6821-6826.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.7.4 CN- CO and COS protect from inhibition; CO, CO2 and COS reverse inhibition Rhodospirillum rubrum
1.2.7.4 COS rapid-equilibrium inhibitor largely competitive versus CO, uncompetitive versus methyl viologen Rhodospirillum rubrum
1.2.7.4 additional information inhibition data are interpreted in terms of two binding sites for CO on CO dehydrogenase Rhodospirillum rubrum

Organism

EC Number Organism UniProt Comment Textmining
1.2.7.4 Rhodospirillum rubrum
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.2.7.4 CO + H2O + 2 oxidized ferredoxin = CO2 + 2 reduced ferredoxin + 2 H+ ping-pong mechanism Rhodospirillum rubrum
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.7.4 CO + H2O + methyl viologen
-
 Rhodospirillum rubrum CO2 + reduced methyl viologen
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.2.7.4 0.0023
-
 COS competitive inhibition vs. CO Rhodospirillum rubrum
1.2.7.4 0.0158
-
 COS noncompetitive inhibition vs. methyl viologen Rhodospirillum rubrum