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Literature summary extracted from

  • Banks, R.B.; Barnett, S.D.
    Tropylium tetrafluoroborate, a novel substrate for aldehyde oxidase (1986), Biochem. Biophys. Res. Commun., 140, 609-615.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.3.1 KCN 46% inhibition at 0.2 mM Oryctolagus cuniculus
1.2.3.1 menadione complete inhibition of tropylium ion oxidation at 0.003 mM Oryctolagus cuniculus
1.2.3.1 Triton X-100 76% inhibition at 0.0008% Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.3.1 1.15
-
 tropylium tetrafluoroborate ferricyanide as electron acceptor Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.2.3.1 Mo5+
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.3.1 additional information Oryctolagus cuniculus enzyme plays an important role in the biotransformation of drugs and xenobiotics, e.g. antiviral, antimalarial and antitumour compounds and nicotine ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.3.1 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.3.1 liver
-
 Oryctolagus cuniculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.3.1 0.063
-
 N1-methylnicotinamide oxidation with ferricyanide as electron acceptor Oryctolagus cuniculus
1.2.3.1 0.155
-
 tropylium ion oxidation with ferricyanide as electron acceptor Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.3.1 additional information enzyme plays an important role in the biotransformation of drugs and xenobiotics, e.g. antiviral, antimalarial and antitumour compounds and nicotine Oryctolagus cuniculus ?
-
 ?
1.2.3.1 N1-methylnicotinamide + H2O + O2 potassium ferricyanide acts as electron acceptor Oryctolagus cuniculus N1-methyl-2-pyridone-5-carboxamide + N1-methyl-4-pyridone-3-carboxamide + H2O2
-
 ?
1.2.3.1 tropylium tetrafluoroborate + H2O + ferricyanide other electron acceptors as dichloroindophenol and chromate Oryctolagus cuniculus tropone + ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.3.1 7.8
-
 assay at Oryctolagus cuniculus