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Literature summary extracted from

  • Rothschild, H.A.; Barron, E.S.
    The oxidation of betaine aldehyde be betaine aldehyde dehydrogenase (1954), J. Biol. Chem., 209, 511-523.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.8 Cys activates, optimal concentration: 1 mM Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.8 acetaldehyde
-
 Rattus norvegicus
1.2.1.8 DL-glyceraldehyde
-
 Rattus norvegicus
1.2.1.8 iodoacetamide
-
 Rattus norvegicus
1.2.1.8 iodoacetate
-
 Rattus norvegicus
1.2.1.8 Iodosobenzoate
-
 Rattus norvegicus
1.2.1.8 methyl(bis-beta-chloroethyl)amine
-
 Rattus norvegicus
1.2.1.8 PCMB
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.8 0.11
-
 Betaine aldehyde
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.8 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.8 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.8 brain
-
 Rattus norvegicus
-
1.2.1.8 heart
-
 Rattus norvegicus
-
1.2.1.8 kidney
-
 Rattus norvegicus
-
1.2.1.8 liver
-
 Rattus norvegicus
-
1.2.1.8 small intestine
-
 Rattus norvegicus
-
1.2.1.8 spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.8 betaine aldehyde + NAD+ + H2O
-
 Rattus norvegicus betaine + NADH
-
 ?
1.2.1.8 betaine aldehyde + NADP+ + H2O no activity with NAD+ Rattus norvegicus betaine + NADPH
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.8 8.8 9.2
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.8 NAD+
-
 Rattus norvegicus