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Literature summary extracted from

  • Thomas, D.; Surdin-Kerjan, Y.
    Structure of the HOM2 gene of Saccharomyces cerevisiae and regulation of its expression (1989), Mol. Gen. Genet., 217, 149-154.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.11 HOM2 gene encodes aspartic semialdehyde dehydrogenase Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.11 39530
-
 4 * 39530, nucleotide sequence analysis of the HOM2 region Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.11 L-4-aspartyl phosphate + NADPH Saccharomyces cerevisiae synthesis of threonine L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?
1.2.1.11 L-4-aspartyl phosphate + NADPH Saccharomyces cerevisiae synthesis of methionine L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.11 Saccharomyces cerevisiae
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.11 additional information
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.11 L-4-aspartyl phosphate + NADPH synthesis of threonine Saccharomyces cerevisiae L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?
1.2.1.11 L-4-aspartyl phosphate + NADPH synthesis of methionine Saccharomyces cerevisiae L-aspartate 4-semialdehyde + phosphate + NADP+
-
 ?
1.2.1.11 L-aspartate 4-semialdehyde + phosphate + NADP+
-
 Saccharomyces cerevisiae L-4-aspartyl phosphate + NADPH
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.11 tetramer 4 * 39530, nucleotide sequence analysis of the HOM2 region Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.11 NADPH
-
 Saccharomyces cerevisiae