BRENDA - Enzyme Database show

Structure of the HOM2 gene of Saccharomyces cerevisiae and regulation of its expression

Thomas, D.; Surdin-Kerjan, Y.; Mol. Gen. Genet. 217, 149-154 (1989)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
1.2.1.11
HOM2 gene encodes aspartic semialdehyde dehydrogenase
Saccharomyces cerevisiae
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.2.1.11
39530
-
4 * 39530, nucleotide sequence analysis of the HOM2 region
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.1.11
L-4-aspartyl phosphate + NADPH
Saccharomyces cerevisiae
synthesis of threonine
L-aspartate 4-semialdehyde + phosphate + NADP+
-
Saccharomyces cerevisiae
-
1.2.1.11
L-4-aspartyl phosphate + NADPH
Saccharomyces cerevisiae
synthesis of methionine
L-aspartate 4-semialdehyde + phosphate + NADP+
-
Saccharomyces cerevisiae
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.2.1.11
Saccharomyces cerevisiae
-
-
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
1.2.1.11
additional information
-
-
Saccharomyces cerevisiae
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.1.11
L-4-aspartyl phosphate + NADPH
synthesis of threonine
390189
Saccharomyces cerevisiae
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
-
1.2.1.11
L-4-aspartyl phosphate + NADPH
synthesis of methionine
390189
Saccharomyces cerevisiae
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
-
1.2.1.11
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
L-4-aspartyl phosphate + NADPH
-
390189
Saccharomyces cerevisiae
-
Subunits
EC Number
Subunits
Commentary
Organism
1.2.1.11
tetramer
4 * 39530, nucleotide sequence analysis of the HOM2 region
Saccharomyces cerevisiae
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.2.1.11
NADPH
-
Saccharomyces cerevisiae
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
1.2.1.11
HOM2 gene encodes aspartic semialdehyde dehydrogenase
Saccharomyces cerevisiae
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.2.1.11
NADPH
-
Saccharomyces cerevisiae
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
1.2.1.11
39530
-
4 * 39530, nucleotide sequence analysis of the HOM2 region
Saccharomyces cerevisiae
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.2.1.11
L-4-aspartyl phosphate + NADPH
Saccharomyces cerevisiae
synthesis of threonine
L-aspartate 4-semialdehyde + phosphate + NADP+
-
Saccharomyces cerevisiae
-
1.2.1.11
L-4-aspartyl phosphate + NADPH
Saccharomyces cerevisiae
synthesis of methionine
L-aspartate 4-semialdehyde + phosphate + NADP+
-
Saccharomyces cerevisiae
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
1.2.1.11
additional information
-
-
Saccharomyces cerevisiae
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.2.1.11
L-4-aspartyl phosphate + NADPH
synthesis of threonine
390189
Saccharomyces cerevisiae
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
-
1.2.1.11
L-4-aspartyl phosphate + NADPH
synthesis of methionine
390189
Saccharomyces cerevisiae
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
-
1.2.1.11
L-aspartate 4-semialdehyde + phosphate + NADP+
-
390189
Saccharomyces cerevisiae
L-4-aspartyl phosphate + NADPH
-
390189
Saccharomyces cerevisiae
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
1.2.1.11
tetramer
4 * 39530, nucleotide sequence analysis of the HOM2 region
Saccharomyces cerevisiae