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Literature summary extracted from
- ACTH-stimulated rabbit adrenal 17alpha-hydroxylase. Kinetic properties and a comparison with those of 3beta-hydroxysteroid dehydrogenase (1978), J. Steroid Biochem., 9, 1033-1041.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.19 | pregnenolone + AH2 + O2 | Oryctolagus cuniculus | - |
17alpha-hydroxypregnenolone + A + H2O | - |
? |  |
| 1.14.14.19 | progesterone + [reduced NADPH-hemoprotein reductase] + O2 | Oryctolagus cuniculus | - |
17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.19 | Oryctolagus cuniculus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.19 | adrenal gland | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.19 | pregnenolone + AH2 + O2 | - |
Oryctolagus cuniculus | 17alpha-hydroxypregnenolone + A + H2O | - |
? | |
| 1.14.14.19 | progesterone + [reduced NADPH-hemoprotein reductase] + O2 | - |
Oryctolagus cuniculus | 17alpha-hydroxyprogesterone + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.14.19 | NADPH | - |
Oryctolagus cuniculus | |
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Release 2023.1 (January 2023)
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