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Literature summary extracted from

  • Abe, I.; Kashiwagi, K.; Noguchi, H.
    Antioxidative galloyl esters as enzyme inhibitors of p-hydroxybenzoate hydroxylase (2000), FEBS Lett., 483, 131-134.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.13.2 expression in Escherichia coli Pseudomonas aeruginosa

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.13.2 (-)-epigallocatechin-3-O-gallate non-competitive, binds to the enzyme in the proximity of the FAD binding site via formation of three hydrogen bonds Pseudomonas aeruginosa
1.14.13.2 n-dodecyl gallate non-competitive Pseudomonas aeruginosa

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.2 Pseudomonas aeruginosa
-
-
-
1.14.13.2 Pseudomonas fluorescens P00438
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.2 4-hydroxybenzoate + NADPH + O2
-
 Pseudomonas aeruginosa protocatechuate + NADP+ + H2O
-
 ?
1.14.13.2 4-hydroxybenzoate + NADPH + O2
-
 Pseudomonas fluorescens protocatechuate + NADP+ + H2O
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.14.13.2 0.014
-
 (-)-epigallocatechin-3-O-gallate
-
 Pseudomonas aeruginosa
1.14.13.2 0.0181
-
 n-dodecyl gallate
-
 Pseudomonas aeruginosa