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Literature summary extracted from

  • Fukui, M.; Fujimoto, T.; Watanabe, K.; Endo, K.; Kuno, K.
    Prostaglandin F synthase is localized to contractile interstitial cells in bovine lung (1996), J. Histochem. Cytochem., 44, 251-257.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.188 expression in Escherichia coli Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.188 Bos taurus
-
 two isozymes, lung-type and liver-type
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.188 lung contractile interstitial cells Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.188 (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate + NADPH
-
 Bos taurus (5Z,13E)-(15S)-9alpha,11beta,15-trihydroxyprosta-5,13-dienoate + NADP+
-
 ?
1.1.1.188 prostaglandin H2 + NADPH + H+
-
 Bos taurus (5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate + NADP+
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.188 NADH less effective than NADPH Bos taurus
1.1.1.188 NADPH
-
 Bos taurus