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Literature summary extracted from

  • Rainwater, D.L.; Kolattukudy, P.E.
    Purification and characterization of acyl-CoA carboxylase from the goose uropygial gland which produces multimethyl-branched acids and evidence for its identity with avian acetyl-CoA carboxylase (1982), Arch. Biochem. Biophys., 213, 372-383.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.4.1.2 citrate maximal stimulation at 20 mM, 3fold Anser anser

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.4.1.2 2-Methyl-2-[p-(1,2,3,4-tetrahydro-1-naphthyl)-phenoxy]propionic acid
-
 Anser anser
6.4.1.2 Cl-
-
 Anser anser
6.4.1.2 Mg2+ about 10 mM Mg2+ required for maximal activity, inhibition above 15 mM Anser anser
6.4.1.2 Na+
-
 Anser anser
6.4.1.2 Phenylglyoxal
-
 Anser anser
6.4.1.2 pyridoxal 5'-phosphate acetyl-CoA protects Anser anser

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.4.1.2 0.1
-
 ATP propionyl-CoA Anser anser
6.4.1.2 0.142
-
 acetyl-CoA
-
 Anser anser
6.4.1.2 0.143
-
 butyryl-CoA
-
 Anser anser

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.4.1.2 Mg2+ about 10 mM Mg2+ required for maximal activity, inhibition above 15 mM Anser anser

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
6.4.1.2 238000
-
 x * 238000, SDS-PAGE Anser anser

Organism

EC Number Organism UniProt Comment Textmining
6.4.1.2 Anser anser
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.4.1.2
-
 Anser anser

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.4.1.2 uropygial gland
-
 Anser anser
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.4.1.2 5
-
-
 Anser anser

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.4.1.2 ATP + acetyl-CoA + HCO3-
-
 Anser anser ADP + phosphate + malonyl-CoA
-
 ?
6.4.1.2 ATP + butyryl-CoA + HCO3-
-
 Anser anser ADP + ethylmalonyl-CoA + phosphate
-
 ?
6.4.1.2 ATP + propionyl-CoA + HCO3-
-
 Anser anser ADP + phosphate + methylmalonyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.4.1.2 ? x * 238000, SDS-PAGE Anser anser

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4.1.2 7.5 8.5
-
 Anser anser