Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Smith, W.L.; DeWitt, D.L.; Day, J.S.
    Purification, quantitation, and localization of PGI2 synthase using monoclonal antibodies (1983), Adv. Prostaglandin Thromboxane Leukot. Res., 11, 87-92.
    View publication on PubMed

Application

EC Number Application Comment Organism
5.3.99.4 medicine formation of monoclonal antibodies against prostacyclin synthase Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.4 13-hydroperoxylinoleic acid rapid inactivation of purified enzyme during incubation with prostaglandin H2 Bos taurus
5.3.99.4 9,11-Azoprosta-5,13-dienoic acid
-
 Bos taurus
5.3.99.4 monoclonal antibodies against prostacyclin synthase Bos taurus
5.3.99.4 prostaglandin H2 rapid inactivation of purified enzyme during incubation with prostaglandin H2 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.3.99.4 microsome
-
 Bos taurus
-
-
5.3.99.4 plasmalemma
-
 Bos taurus
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.3.99.4 52000
-
 x * 52000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.4 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.3.99.4
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.4 aorta
-
 Bos taurus
-
5.3.99.4 endothelium
-
 Bos taurus
-
5.3.99.4 smooth muscle vascular and nonvascular Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.4 Prostaglandin H2
-
 Bos taurus Prostaglandin I2 prostaglandin I2 ?

Subunits

EC Number Subunits Comment Organism
5.3.99.4 ? x * 52000, SDS-PAGE Bos taurus