BRENDA - Enzyme Database show

Preparation and assay of prostacyclin synthase

Salmon, J.A.; Flower, R.J.; Methods Enzymol. 86, 91-99 (1982)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.4
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid
-
Sus scrofa
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.4
Sus scrofa
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
5.3.99.4
partial
Sus scrofa
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
artery
vascular
Sus scrofa
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.3.99.4
additional information
-
assay methods
Sus scrofa
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
prostaglandin G2
-
37464
Sus scrofa
prostaglandin I2 + 15-hydroperoxyprostacyclin
15-hydroperoxyprostacyclin decomposes to 6,15-diketo-prostaglandin F1alpha
37464
Sus scrofa
-
5.3.99.4
Prostaglandin H2
-
37464
Sus scrofa
Prostaglandin I2
prostaglandin I2
37464
Sus scrofa
-
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.3.99.4
6.8
7.5
-
Sus scrofa
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.4
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid
-
Sus scrofa
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
5.3.99.4
partial
Sus scrofa
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
artery
vascular
Sus scrofa
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
5.3.99.4
additional information
-
assay methods
Sus scrofa
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
prostaglandin G2
-
37464
Sus scrofa
prostaglandin I2 + 15-hydroperoxyprostacyclin
15-hydroperoxyprostacyclin decomposes to 6,15-diketo-prostaglandin F1alpha
37464
Sus scrofa
-
5.3.99.4
Prostaglandin H2
-
37464
Sus scrofa
Prostaglandin I2
prostaglandin I2
37464
Sus scrofa
-
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5.3.99.4
6.8
7.5
-
Sus scrofa