BRENDA - Enzyme Database show

Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase

Ullrich, V.; Castle, L.; Weber, P.; Biochem. Pharmacol. 30, 2033-2036 (1981)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.4
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid
-
Sus scrofa
5.3.99.4
Tranylcypromine
-
Sus scrofa
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.4
microsome
-
Sus scrofa
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.4
Sus scrofa
-
-
-
Reaction
EC Number
Reaction
Commentary
Organism
5.3.99.4
(5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
prostaglandin endoperoxyde PGH2 prostacyclin PGI2 , a mechanism with the participation of a heme-thiolate protein is proposed
Sus scrofa
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
aorta
-
Sus scrofa
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
37463
Sus scrofa
Prostaglandin I2
prostaglandin I2
37463
Sus scrofa
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.4
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid
-
Sus scrofa
5.3.99.4
Tranylcypromine
-
Sus scrofa
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.4
microsome
-
Sus scrofa
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
aorta
-
Sus scrofa
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
37463
Sus scrofa
Prostaglandin I2
prostaglandin I2
37463
Sus scrofa
-