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Literature summary extracted from
- Influence of human low density and high density lipoprotein cholesterol on the in vitro prostaglandin I2 synthetase activity (1980), Biochim. Biophys. Acta, 620, 352-355.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.99.4 | High density lipoprotein cholesterol | 1.0 mg/ml stimulates 21%. Lower concentrations inhibit, 16% inhibition by 0.25 mg/ml | Sus scrofa | |
| 5.3.99.4 | Low density lipoprotein cholesterol | 0.5 mg/ml stimulates 27%. Inhibition at higher concentrations | Sus scrofa |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.3.99.4 | Low density lipoprotein cholesterol | 0.5 mg/ml stimulates 27%. Inhibition at higher concentrations. Maximal inhibition by 2 mg/ml, 64.2% | Sus scrofa |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 5.3.99.4 | microsome | - |
Sus scrofa | - |
- |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.3.99.4 | Sus scrofa | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.3.99.4 | aorta | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.3.99.4 | Prostaglandin H2 | - |
Sus scrofa | Prostaglandin I2 | prostaglandin I2 | ? |  |
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Release 2023.1 (January 2023)
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