BRENDA - Enzyme Database show

Peroxidase-dependent deactivation of prostacyclin synthetase

Ham, E.A.; Egan, R.W.; Soderman, D.D.; Gale, P.H.; Kuehl, F.A.; J. Biol. Chem. 254, 2191-2194 (1979)

Data extracted from this reference:

Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.4
microsome
-
Ovis aries
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.4
Ovis aries
-
ram
-
Oxidation Stability
EC Number
Oxidation Stability
Organism
5.3.99.4
destructive action of a nascent oxidizing agent released from prostaglandin G1, 15-hydroperoxy-prostaglandin E1, 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid is prevented by 2-aminomethyl-4-tert-6-iodophenol
Ovis aries
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
seminal vesicle
-
Ovis aries
-
Storage Stability
EC Number
Storage Stability
Organism
5.3.99.4
-90°C, gradual loss of activity of enzyme in crude extract
Ovis aries
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
37459
Ovis aries
Prostaglandin I2
prostaglandin I2
37459
Ovis aries
-
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
5.3.99.4
microsome
-
Ovis aries
-
-
Oxidation Stability (protein specific)
EC Number
Oxidation Stability
Organism
5.3.99.4
destructive action of a nascent oxidizing agent released from prostaglandin G1, 15-hydroperoxy-prostaglandin E1, 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid is prevented by 2-aminomethyl-4-tert-6-iodophenol
Ovis aries
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.4
seminal vesicle
-
Ovis aries
-
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
5.3.99.4
-90°C, gradual loss of activity of enzyme in crude extract
Ovis aries
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.4
Prostaglandin H2
-
37459
Ovis aries
Prostaglandin I2
prostaglandin I2
37459
Ovis aries
-