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Literature summary extracted from
- The reaction mechanism of rat liver glyoxalase I and its inhibition by MS-3 (1976), Agric. Biol. Chem., 40, 559-566.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.4.1.5 | MS-3 | inhibitor produced by a mushroom Stereum hirsutum; mechanism of inhibition | Rattus norvegicus |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.4.1.5 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.4.1.5 | 18.7 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.4.1.5 | glutathione + methylglyoxal | the hemimercaptal adduct produced nonenzymatically from methylglyoxal and glutathione is the substrate | Rattus norvegicus | S-lactoylglutathione | - |
? | |
| 4.4.1.5 | glutathione + methylglyoxal | the substrat is the hemithioacetal of methylglyoxal and glutathione | Rattus norvegicus | S-lactoylglutathione | - |
? | |
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Release 2023.1 (January 2023)
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