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Literature summary extracted from

  • Barelli, H.; Vincent, J.P.; Checler, F.
    Rat kidney endopeptidase 24.16. Purification, physico-chemical characteristics and differential specificity towards opiates, tachykinins and neurotensin-related peptides (1993), Eur. J. Biochem., 211, 79-90.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.16 1,10-phenanthroline
-
 Rattus norvegicus
3.4.24.16 carboxyphenylethyl-Ala-Ala-Phe-4-aminobenzoate
-
 Rattus norvegicus
3.4.24.16 carboxyphenylethyl-Ala-Ala-Tyr-4-aminobenzoate
-
 Rattus norvegicus
3.4.24.16 Cu2+
-
 Rattus norvegicus
3.4.24.16 dithiothreitol
-
 Rattus norvegicus
3.4.24.16 EDTA
-
 Rattus norvegicus
3.4.24.16 Zn2+
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.16 membrane the enzyme is not attached by a glycosyl-phosphatidylinositol anchor in the emembrane, the enzyme can not be released from the membrane upon trypsinolysis Rattus norvegicus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.16 70000
-
 1 * 70000, SDS-PAGE Rattus norvegicus
3.4.24.16 70000 75000 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.16 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.16
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.16 kidney
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.16 0.0091
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.16 Arg-Arg-Pro-Tyr-Ile-Leu + H2O
-
 Rattus norvegicus Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 + H2O
-
 Rattus norvegicus Arg-Pro-Lys-Pro-Gln + Gln-Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro-Gln-Gln + Phe-Phe-Gly-Leu-Met-NH2 + Arg-Pro-Lys-Pro
-
 ?
3.4.24.16 pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu + H2O
-
 Rattus norvegicus pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro + Tyr-Ile-Leu
-
 ?
3.4.24.16 Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile + H2O
-
 Rattus norvegicus Tyr-Gly-Gly-Phe-Leu + Arg-Arg-Ile
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.24.16 monomer 1 * 70000, SDS-PAGE Rattus norvegicus