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Literature summary extracted from

  • Barelli, H.; Vincent, J.P.; Checler, F.
    Peripheral inactivation of neurotensin. Isolation and characterization of a metallopeptidase from rat ileum (1988), Eur. J. Biochem., 175, 481-489.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.16 1,10-phenanthroline
-
 Rattus norvegicus
3.4.24.16 acetyl-neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 acetyl-neurotensin(8-13)aminde degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 carboxy-2-phenylethyl-Ala-Ala-Phe-4-aminobenzoate
-
 Rattus norvegicus
3.4.24.16 Co2+
-
 Rattus norvegicus
3.4.24.16 Cu2+
-
 Rattus norvegicus
3.4.24.16 dithiothreitol
-
 Rattus norvegicus
3.4.24.16 EDTA reactivation by Zn2+ Rattus norvegicus
3.4.24.16 neurotensin inhibits degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 neurotensin(9-13)
-
 Rattus norvegicus
3.4.24.16 Pro-Xaa dipeptides most potent inhibitors, Xaa-Pro dipeptides are ineffective Rattus norvegicus
3.4.24.16 Zn2+
-
 Rattus norvegicus
3.4.24.16 [acetylPhe12]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Ala12]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Ala13]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Arg8]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Arg9]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Leu11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Phe11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Trp11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Tyr11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [D-Tyr3]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Dopa11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [His11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [naphthylalanyl11]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Phe11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Ser11]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Thr11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Trp11]neurotensin degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Tyr-ethyl ester11]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus
3.4.24.16 [Tyr13]neurotensin(8-13) degradation of tritiated neurotensin Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.24.16 70000 75000 gel filtration Rattus norvegicus
3.4.24.16 75000
-
 1 * 75000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.16 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.16
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.16 ileum
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.24.16 0.104
-
-
 Rattus norvegicus

Subunits

EC Number Subunits Comment Organism
3.4.24.16 monomer 1 * 75000, SDS-PAGE Rattus norvegicus