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Literature summary extracted from

  • Tuderman, L.; Prockop, D.J.
    Procollagen N-proteinase. Properties of the enzyme purified from chick embryo tendons (1982), Eur. J. Biochem., 125, 545-549.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.24.14 1,10-phenanthroline 45% inhibition at 0.1 mM Gallus gallus
3.4.24.14 2,2'-dipyridyl 57% inhibition at 1 mM Gallus gallus
3.4.24.14 2-mercaptoethanol 81% inhibition at 1150 mM Gallus gallus
3.4.24.14 Co2+
-
 Gallus gallus
3.4.24.14 Cu2+
-
 Gallus gallus
3.4.24.14 dithiothreitol 77% inhibition at 0.5 mM Gallus gallus
3.4.24.14 EDTA 100% inhibition at 2.5 mM Gallus gallus
3.4.24.14 Fe2+
-
 Gallus gallus
3.4.24.14 Mg2+ 64% inhibition at 5 mM Gallus gallus
3.4.24.14 Mn2+ 49% inhibition at 5 mM Gallus gallus
3.4.24.14 Pb2+
-
 Gallus gallus
3.4.24.14 Zn2+
-
 Gallus gallus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.14 0.0003 0.0005 pNcollagen I
-
 Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.14 Ca2+ required for maximal activity Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.14 procollagen I + H2O Gallus gallus
-
 ?
-
 ?
3.4.24.14 procollagen II + H2O Gallus gallus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.14 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.14
-
 Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.14 tendon
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.14 pNcollagen I + H2O
-
 Gallus gallus ?
-
 ?
3.4.24.14 procollagen I + H2O not procollagen III Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen I + H2O not procollagen IV Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen I + H2O substrate must be in native state Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen I + H2O
-
 Gallus gallus ?
-
 ?
3.4.24.14 procollagen II + H2O substrate must be in native state Gallus gallus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
3.4.24.14 procollagen II + H2O
-
 Gallus gallus ?
-
 ?