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Literature summary extracted from

  • Pohl, J.; Bures, L.; Slavik, K.
    Isolation and characterization of cathepsin D from human gasttric mucosa (1981), Collect. Czech. Chem. Commun., 46, 3302-3313.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.23.5 Diazoacetyl-DL-norleucine methyl ester
-
 Homo sapiens
3.4.23.5 Diazoacetylglycine ethyl ester
-
 Homo sapiens
3.4.23.5 inhibitor isolated from potatoes
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.23.5 1.1
-
 Glu-Glu-His-Phe-Phe-Ala-Leu-methyl ester
-
 Homo sapiens
3.4.23.5 1.6
-
 Glu-Glu-His-Phe-Phe-Ala-Ala
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.23.5 18000
-
 1 * 18000 + 1 * 33000, SDS-PAGE Homo sapiens
3.4.23.5 33000
-
 1 * 18000 + 1 * 33000, SDS-PAGE Homo sapiens
3.4.23.5 49000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.5 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.23.5 side-chain modification glycoprotein Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.23.5
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.23.5 gastric mucosa
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.23.5 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.5 Glu-Glu-His-Phe-Phe-Ala-Ala + H2O
-
 Homo sapiens ?
-
 ?
3.4.23.5 Glu-Glu-His-Phe-Phe-Ala-Leu-methyl ester + H2O
-
 Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.23.5 dimer 1 * 18000 + 1 * 33000, SDS-PAGE Homo sapiens

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.23.5 0.4
-
 Glu-Glu-His-Phe-Phe-Ala-Ala
-
 Homo sapiens
3.4.23.5 2.1
-
 Glu-Glu-His-Phe-Phe-Ala-Leu-methyl ester
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.23.5 3.2 3.6 hemoglobin Homo sapiens