Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Cunningham, M.; Tang, J.
    Purification and properties of cathepsin D from porcine spleen (1976), J. Biol. Chem., 251, 4528-4536.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.4.23.5 stable upon freezing Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.23.5 1,2-epoxy-3-(4-nitrophenoxy)propane
-
 Sus scrofa
3.4.23.5 Diazoacetyl-DL-norleucine methyl ester
-
 Sus scrofa
3.4.23.5 ethanol 5% Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.5 Sus scrofa
-
 pig
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.23.5
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.23.5 spleen
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.5 Hemoglobin + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.5 insulin + H2O oxidized A chain and B chain Sus scrofa ?
-
 ?
3.4.23.5 peptide D + H2O
-
 Sus scrofa ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.23.5 ? x * 34000-35000, SDS-PAGE Sus scrofa

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.23.5 50
-
 stable up to Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.23.5 2.9
-
 0.1 M sodium acetate or formate buffer, hydrolysis of hemoglobin Sus scrofa
3.4.23.5 3.4
-
 2 pH-optima: at pH 3.4 and at pH 3.8, 0.5 M sodium acetate or formate buffer, hydrolysis of hemoglobin Sus scrofa
3.4.23.5 3.8
-
 2 pH-optima: at pH 3.4 and at pH 3.8, 0.5 M sodium acetate or formate buffer, hydrolysis of hemoglobin Sus scrofa