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Literature summary extracted from

  • Auffret, C.A.; Ryle, A.P.
    The catalytic activity of pig pepsin C towards small synthetic substrates (1979), Biochem. J., 179, 239-246.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.23.3 Acetyl-Phe hydrolysis of acetyl-Phe-Leu-Val-His-amide Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.23.3 0.28
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-0.15 mM Sus scrofa
3.4.23.3 0.7
-
 acetyl-Ala-Phe-Leu-Val-His-NH2
-
 Sus scrofa
3.4.23.3 0.82
-
 acetyl-Tyr-Leu-Val-His-OH
-
 Sus scrofa
3.4.23.3 0.82
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-0.5 mM Sus scrofa
3.4.23.3 1.71
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-1.0 mM Sus scrofa
3.4.23.3 1.84
-
 acetyl-Phe-Leu-Val-His-NH2
-
 Sus scrofa
3.4.23.3 1.84
-
 acetyl-Phe-Leu-Val-His methyl ester
-
 Sus scrofa
3.4.23.3 4.31
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-2.0 mM Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.3 Sus scrofa
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.3 acetyl-Ala-Leu-Val-His-NH2 + H2O very low activity Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Ala-Leu-Val-His-OH + H2O very low activity Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Ala-Phe-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Phe-Leu-Val-His methyl ester + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Phe-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Tyr-Leu-Val-His methyl ester + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Tyr-Leu-Val-His-NH2 + H2O
-
 Sus scrofa ?
-
 ?
3.4.23.3 acetyl-Tyr-Leu-Val-His-OH + H2O
-
 Sus scrofa ?
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.23.3 1.06
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-0.15 mM Sus scrofa
3.4.23.3 1.07
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-0.5 mM Sus scrofa
3.4.23.3 1.08
-
 acetyl-Tyr-Leu-Val-His-NH2
-
 Sus scrofa
3.4.23.3 4.45
-
 acetyl-Tyr-Leu-Val-His-NH2 Km-value for the range 0.1-2.0 mM Sus scrofa
3.4.23.3 5.13
-
 acetyl-Phe-Leu-Val-His methyl ester
-
 Sus scrofa
3.4.23.3 5.76
-
 acetyl-Tyr-Leu-Val-His methyl ester Km-value for the range 0.025-1.0 mM Sus scrofa
3.4.23.3 6.12
-
 acetyl-Phe-Leu-Val-His-NH2
-
 Sus scrofa
3.4.23.3 7.01
-
 acetyl-Ala-Phe-Leu-Val-His-NH2
-
 Sus scrofa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.23.3 additional information
-
-
 Sus scrofa