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Literature summary extracted from

  • Evans, P.; Etherington, D.J.
    Characterisation of cathepsin B and collagenolytic cathepsin from human placenta (1978), Eur. J. Biochem., 83, 87-97.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.22.1 thiol compounds required for full activity Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.1 2,2'-dipyridyl disulfide
-
 Homo sapiens
3.4.22.1 antipain
-
 Homo sapiens
3.4.22.1 Hg2+
-
 Homo sapiens
3.4.22.1 iodoacetic acid
-
 Homo sapiens
3.4.22.1 leupeptin
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.1 24500
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.1 Proteins + H2O Homo sapiens
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.22.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.1 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.1 Arg-beta-naphthylamide + H2O
-
 Homo sapiens Arg + beta-naphthylamine
-
 ?
3.4.22.1 benzoyl-DL-Arg-p-nitroanilide + H2O
-
 Homo sapiens benzoyl-DL-Arg + p-nitroaniline
-
 ?
3.4.22.1 benzyloxycarbonyl-Ala-4-nitrophenyl ester + H2O
-
 Homo sapiens benzyloxycarbonyl-Ala + 4-nitrophenol
-
 ?
3.4.22.1 benzyloxycarbonyl-Gly-4-nitrophenyl ester + H2O
-
 Homo sapiens benzyloxycarbonyl-Gly + 4-nitrophenol
-
 ?
3.4.22.1 benzyloxycarbonyl-Lys-4-nitrophenyl ester + H2O
-
 Homo sapiens benzyloxycarbonyl-Lys + 4-nitrophenol
-
 ?
3.4.22.1 Collagen + H2O
-
 Homo sapiens Hydrolyzed collagen
-
 ?
3.4.22.1 Proteins + H2O
-
 Homo sapiens ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.22.1 3.3
-
 collagen as substrate Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.22.1 2.5 4 collagen as substrate Homo sapiens