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Literature summary extracted from

  • Virca, G.D.; Metz, G.; Schnebli, H.P.
    Similarities between human and rat leukocyte elastase and cathepsin G (1984), Eur. J. Biochem., 144, 1-9.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.4.21.20 autolysis Homo sapiens
3.4.21.20 autolysis Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.20 Eglin c
-
 Homo sapiens
3.4.21.20 Eglin c
-
 Rattus norvegicus
3.4.21.20 additional information inhibitors from soybean and lima-bean Homo sapiens
3.4.21.20 additional information inhibitors from soybean and lima-bean Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.21.20 0.52
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Rattus norvegicus
3.4.21.20 1.49
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.20 Homo sapiens
-
-
-
3.4.21.20 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Storage Stability

EC Number Storage Stability Organism
3.4.21.20 -20°C, lyophilized Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.20 methoxy succinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.20 methoxy succinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.21.20 N-acetyl-L-Phe-p-nitrophenyl ester + H2O
-
 Homo sapiens ?
-
 ?
3.4.21.20 N-acetyl-L-Phe-p-nitrophenyl ester + H2O
-
 Rattus norvegicus ?
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.21.20 6
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitroanilide
-
 Homo sapiens
3.4.21.20 16.5
-
 methoxysuccinyl-L-alanine-L-alanine-L-proline-L-valine-p-nitrophenylanilide
-
 Rattus norvegicus
3.4.21.20 20.2
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Rattus norvegicus
3.4.21.20 68.3
-
 N-acetyl-L-phenylalanine-p-nitrophenyl ester
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.20 6.8
-
-
 Homo sapiens
3.4.21.20 8.4
-
-
 Rattus norvegicus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.4.21.20 5.8 8 more than 50% of maximal activity at pH 5.8 and pH 8.0 Homo sapiens
3.4.21.20 6.6 8.4 pH 6.6: more than 50% of maximal activity, pH 8.4: optimum Rattus norvegicus