EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.17.2 | 6-amino-n-hexanoic acid | - |
Homo sapiens | |
3.4.17.2 | Co2+ | hydrolysis of hippuryl-L-Arg | Homo sapiens | |
3.4.17.2 | EDTA | partial | Homo sapiens | |
3.4.17.2 | SDS | - |
Homo sapiens | |
3.4.17.2 | Urea | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.17.2 | 0.05 | - |
hippuryl-L-Arg | carboxypeptidase B I | Homo sapiens | |
3.4.17.2 | 0.071 | - |
hippuryl-L-Arg | carboxypeptidase B II | Homo sapiens | |
3.4.17.2 | 0.277 | - |
hippuryl-Arg | carboxypeptidase B I | Homo sapiens | |
3.4.17.2 | 0.31 | - |
hippuryl-Arg | carboxypeptidase B II | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.17.2 | Co2+ | CoCl2, accelerates hydrolysis of hippuryl-L-Arg and hippuryl-Lys | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.4.17.2 | 32210 | - |
carboxypeptidase B II, gel filtration | Homo sapiens |
3.4.17.2 | 32920 | - |
carboxypeptidase B I, gel filtration | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.17.2 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.17.2 | - |
Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.17.2 | pancreas | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.4.17.2 | 862 | - |
carboxypeptidase B I | Homo sapiens |
3.4.17.2 | 1192 | - |
carboxypeptidase B II | Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.17.2 | hippuryl-L-Arg | - |
Homo sapiens | hippuric acid + L-Arg | - |
? | |
3.4.17.2 | hippuryl-Lys + H2O | peptidase activity | Homo sapiens | hippuric acid + Lys | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.17.2 | 7 | - |
cleavage of hippuryl-L-Arg | Homo sapiens |
3.4.17.2 | 10 | - |
hydrolysis of hippuryl-L-Arg | Homo sapiens |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.4.17.2 | 6 | 10 | pH 6: about 60% of maximal activity with carboxypeptidase B I, about 50% of maximal activity with carboxypeptidase B II, pH 10: about 70% of maximal activity with carboxypeptidase B I, about 60% of maximal activity with carboxypeptidase B II, cleavage of hippuryl-L-Arg | Homo sapiens |
3.4.17.2 | 7 | 10.5 | pH 7: about 45% of maximal activity with carboxypeptidase B I, about 30% of maximal activity with carboxypeptidase B II, pH: 10.5: about 90% of maximal activity with carboxypeptidase B I, about 80% of maximal activity with carboxypeptidase B II, hydrolysis of hippuryl-L-Arg | Homo sapiens |