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Literature summary extracted from

  • Wu, Z.; Walsh, C.
    Dithiol compounds: Potent, time-dependent inhibitors of VanX, a zinc-dependent D,D-dipeptidase required for vancomycin resistance in Enterococcus faecium (1996), J. Am. Chem. Soc., 118, 1785-1786.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.16.4 1,2-Ethanedithiol
-
 Enterococcus faecium
3.4.16.4 1,3-propanedithiol
-
 Enterococcus faecium
3.4.16.4 2,3-dimercapto-1-propane-sulfonic acid
-
 Enterococcus faecium
3.4.16.4 2,3-dimercapto-1-propanol
-
 Enterococcus faecium
3.4.16.4 D-cysteine
-
 Enterococcus faecium
3.4.16.4 dithiothreitol
-
 Enterococcus faecium
3.4.16.4 L-cysteine
-
 Enterococcus faecium
3.4.16.4 Mercaptosuccinic acid
-
 Enterococcus faecium
3.4.16.4 additional information inhibition studies Enterococcus faecium
3.4.16.4 thiosalicylic acid
-
 Enterococcus faecium

Organism

EC Number Organism UniProt Comment Textmining
3.4.16.4 Enterococcus faecium
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.16.4 D-Ala-D-Ala + H2O
-
 Enterococcus faecium D-Ala + D-Ala
-
 ?
3.4.16.4 additional information not D-Ala-D-lactate Enterococcus faecium ?
-
 ?