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Literature summary extracted from

  • Abe, I.; Sankawa, U.; Ebizuka, Y.
    Purification and properties of squalene-2,3-epoxide cyclase from pea seedlings (1992), Chem. Pharm. Bull., 40, 1755-1760.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.99.8 sodium deoxycholate the enzyme requires Triton X-100 or deoxycholate for maximal activity Pisum sativum
5.4.99.8 Triton X-100 the enzyme requires Triton X-100 or deoxycholate for maximal activity Pisum sativum

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.99.8 NEM
-
 Pisum sativum
5.4.99.8 p-chloromercuribenzene sulfonic acid
-
 Pisum sativum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.4.99.8 0.025
-
 (S)-2,3-epoxysqualene
-
 Pisum sativum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
5.4.99.8 55000
-
 2 * 55000, SDS-PAGE Pisum sativum

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.8 Pisum sativum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.99.8
-
 Pisum sativum

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.99.8 seedling
-
 Pisum sativum
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.4.99.8 additional information
-
-
 Pisum sativum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.8 (S)-2,3-Epoxysqualene
-
 Pisum sativum Cycloartenol
-
 ?

Subunits

EC Number Subunits Comment Organism
5.4.99.8 dimer 2 * 55000, SDS-PAGE Pisum sativum

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
5.4.99.8 6.5 7.5
-
 Pisum sativum