Literature summary extracted from

Miura, S.; Song, I.S.; Morita, A.; Erickson, R.H.; Kim, Y.S.
Distribution and biosynthesis of aminopeptidase N and dipeptidyl aminopeptidase IV in rat small intestine (1983), Biochim. Biophys. Acta, 761, 66-75.

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.14.5	Rattus norvegicus	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
3.4.14.5	additional information	two-fold activation of precursor enzyme form occurs during transfer from the Golgi membranes to the brush border membranes	Rattus norvegicus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.14.5	small intestine	maximally expressed in mid-villus cells, substantial activity in the crypt cells, primarily associated with brush border membranes in all segments, in the proximal intestine, a significant amount of the enzyme is associated with the cytosol fraction. Cytosol and brush border membrane forms are immunologically identical	Rattus norvegicus	-

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Release 2023.1 (January 2023)