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Literature summary extracted from

  • Jolidon, S.; Polak, A.M.; Guerry, P.; Hartman, P.G.
    Inhibitors of 2,3-oxidosqualene lanosterol-cyclase as potential antifungal agents (1990), Biochem. Soc. Trans., 18, 47-48.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.99.7 19-Azasqualene
-
Candida albicans
5.4.99.7 19-Azasqualene
-
Rattus norvegicus
5.4.99.7 Iminosqualene
-
Candida albicans
5.4.99.7 Iminosqualene
-
Rattus norvegicus
5.4.99.7 additional information antifungal activity of lanosterol synthase inhibitors Candida albicans
5.4.99.7 additional information
-
Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
5.4.99.7 Candida albicans
-
-
-
5.4.99.7 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.99.7 liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.99.7 (S)-squalene-2,3-epoxide
-
Rattus norvegicus Lanosterol
-
?
5.4.99.7 (S)-squalene-2,3-epoxide
-
Candida albicans Lanosterol
-
?