BRENDA - Enzyme Database

Characterization of aminopeptidase B: substrate specificity and affector studies

Hopsu, V.K.; Maekinen, K.K.; Glenner, G.G.; Arch. Biochem. Biophys. 114, 567-575 (1966)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.4.11.6
1,10-phenanthroline
-
Rattus norvegicus
3.4.11.6
2,4-dinitrofluorobenzene
-
Rattus norvegicus
3.4.11.6
2-mercaptoethanol
-
Rattus norvegicus
3.4.11.6
Acetate buffer
-
Rattus norvegicus
3.4.11.6
Borate
-
Rattus norvegicus
3.4.11.6
Borax-pyruvic acid buffer
-
Rattus norvegicus
3.4.11.6
citric acid-sodium citrate buffer
-
Rattus norvegicus
3.4.11.6
ethyliodoacetate
-
Rattus norvegicus
3.4.11.6
glutathione
high concentration
Rattus norvegicus
3.4.11.6
Iodobenzoate
-
Rattus norvegicus
3.4.11.6
p-chloromercuribenzoate
-
Rattus norvegicus
3.4.11.6
phosphate
-
Rattus norvegicus
3.4.11.6
Porphyrindine
-
Rattus norvegicus
3.4.11.6
thioglycolic acid
-
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.4.11.6
Rattus norvegicus
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.4.11.6
L-Arg-2-naphthylamide + H2O
-
35998
Rattus norvegicus
L-Arg + 2-naphthylamine
-
-
-
?
3.4.11.6
L-Arg-peptide + H2O
specific for N-terminal Arg or Lys residues, di-, tri-, and polypeptides
35998
Rattus norvegicus
L-Arg + peptide
-
-
-
?
3.4.11.6
L-Lys-peptide + H2O
specific for N-terminal Arg or Lys residues, di-, tri-, and polypeptide
35998
Rattus norvegicus
L-Lys + peptide
-
-
-
?
3.4.11.6
Lys-2-naphthylamide + H2O
-
35998
Rattus norvegicus
Lys + 2-naphthylamine
-
-
-
?
Temperature Stability [°C]
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.4.11.6
60
-
complete inactivation
Rattus norvegicus
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.4.11.6
7
-
-
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.4.11.6
1,10-phenanthroline
-
Rattus norvegicus
3.4.11.6
2,4-dinitrofluorobenzene
-
Rattus norvegicus
3.4.11.6
2-mercaptoethanol
-
Rattus norvegicus
3.4.11.6
Acetate buffer
-
Rattus norvegicus
3.4.11.6
Borate
-
Rattus norvegicus
3.4.11.6
Borax-pyruvic acid buffer
-
Rattus norvegicus
3.4.11.6
citric acid-sodium citrate buffer
-
Rattus norvegicus
3.4.11.6
ethyliodoacetate
-
Rattus norvegicus
3.4.11.6
glutathione
high concentration
Rattus norvegicus
3.4.11.6
Iodobenzoate
-
Rattus norvegicus
3.4.11.6
p-chloromercuribenzoate
-
Rattus norvegicus
3.4.11.6
phosphate
-
Rattus norvegicus
3.4.11.6
Porphyrindine
-
Rattus norvegicus
3.4.11.6
thioglycolic acid
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.4.11.6
L-Arg-2-naphthylamide + H2O
-
35998
Rattus norvegicus
L-Arg + 2-naphthylamine
-
-
-
?
3.4.11.6
L-Arg-peptide + H2O
specific for N-terminal Arg or Lys residues, di-, tri-, and polypeptides
35998
Rattus norvegicus
L-Arg + peptide
-
-
-
?
3.4.11.6
L-Lys-peptide + H2O
specific for N-terminal Arg or Lys residues, di-, tri-, and polypeptide
35998
Rattus norvegicus
L-Lys + peptide
-
-
-
?
3.4.11.6
Lys-2-naphthylamide + H2O
-
35998
Rattus norvegicus
Lys + 2-naphthylamine
-
-
-
?
Temperature Stability [°C] (protein specific)
EC Number
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
3.4.11.6
60
-
complete inactivation
Rattus norvegicus
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.4.11.6
7
-
-
Rattus norvegicus