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Literature summary extracted from

  • Ishiura, S.; Yamamoto, T.; Yamamoto, M.; Nojima, M.; Aoyagi, T.; Sugita, H.
    Human skeletal muscle contains two major aminopeptidases: an anion-activated aminopeptidase B and an aminopeptidase M-like enzyme (1987), J. Biochem., 102, 1023-1031.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.11.6 diphosphate activation in presence of low Cl- concentrations Homo sapiens
3.4.11.6 phosphate activation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.6 1,10-phenanthroline activity restored by Co2+ Homo sapiens
3.4.11.6 arphamenine A
-
 Homo sapiens
3.4.11.6 Arphamenine B
-
 Homo sapiens
3.4.11.6 p-chloromercuribenzoate
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.11.6 cytosol
-
 Homo sapiens 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.6 Cl- required for activity Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.6 72000 75000 SDS-PAGE, HPLC Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.6 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.6
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.6 skeletal muscle
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.6 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.6 Arg-4-methylcoumarin 7-amide + H2O
-
 Homo sapiens Arg + 7-amino-4-methylcoumarin
-
 ?
3.4.11.6 Lys-4-methylcoumarin 7-amide + H2O
-
 Homo sapiens Lys + 7-amino-4-methylcoumarin
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.6 7
-
-
 Homo sapiens