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Literature summary extracted from

  • Hayashi, M.; Oshima, K.
    Isolation and characterization of aminotripeptidase from monkey brain (1980), J. Biochem., 87, 1403-1411.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.4 1,10-phenanthroline
-
 Macaca fuscata
3.4.11.4 bestatin
-
 Macaca fuscata
3.4.11.4 EDTA
-
 Macaca fuscata
3.4.11.4 EGTA
-
 Macaca fuscata
3.4.11.4 N-ethylmaleimide
-
 Macaca fuscata
3.4.11.4 p-chloromercuribenzoate
-
 Macaca fuscata
3.4.11.4 tosyl-L-lysine-chloromethylketone
-
 Macaca fuscata
3.4.11.4 Zn2+
-
 Macaca fuscata

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.4 0.25
-
 Leu-Gly-Gly
-
 Macaca fuscata
3.4.11.4 0.33
-
 Phe-Gly-Gly
-
 Macaca fuscata

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.4 65000
-
 gel filtration Macaca fuscata

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.4 Macaca fuscata
-
 japanese monkey
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.4
-
 Macaca fuscata

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.4 brain
-
 Macaca fuscata
-

Storage Stability

EC Number Storage Stability Organism
3.4.11.4 -20°C, 0.01 M potassium phosphate buffer, pH 7.0 Macaca fuscata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.4 L-Phe-Gly-Gly + H2O
-
 Macaca fuscata L-Phe + Gly-Gly
-
 ?
3.4.11.4 Leu-Gly-Gly + H2O Tyr Macaca fuscata Leu + Gly-Gly
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.4.11.4 37
-
 slow inactivation above Macaca fuscata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.4 7.5
-
-
 Macaca fuscata