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Literature summary extracted from

  • Itoh, C.; Watanabe, M.; Nagamatsu, A.; Soeda, S.; Kawarabayashi, T.; Shimeno, H.
    Two molecular species of oxytocinase (L-cystine aminopeptidase) in human placenta: purification and characterization (1997), Biol. Pharm. Bull., 20, 20-24.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.3 1,10-phenanthroline
-
 Homo sapiens
3.4.11.3 amastatin CAP II Homo sapiens
3.4.11.3 EDTA
-
 Homo sapiens
3.4.11.3 L-methionine form I inhibited, form II slightly activated Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.3 0.0056
-
 S-benzyl-L-cysteine-p-nitroanilide CAP-I Homo sapiens
3.4.11.3 0.038
-
 S-benzyl-L-cysteine-p-nitroanilide CAP-II Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.3 Co2+ stimulates Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.3 40000
-
 1 * 56000 + 1 * 40000, SDS-PAGE Homo sapiens
3.4.11.3 56000
-
 1 * 56000 + 1 * 40000, SDS-PAGE Homo sapiens
3.4.11.3 61000
-
 CAP-I, 1 * 61000, SDS-PAGE Homo sapiens
3.4.11.3 64000
-
 CAP-I, gel filtration Homo sapiens
3.4.11.3 97000
-
 CAP-II, gel filtratrion Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Homo sapiens
-
 two forms CAP-I and CAP-II
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.3 two forms, CAP-I and CAP-II Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.3 additional information broad specificity Homo sapiens ?
-
 ?
3.4.11.3 S-benzyl-L-cysteine-p-nitroanilide + H2O
-
 Homo sapiens S-benzyl-L-cysteine + p-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.3 dimer 1 * 56000 + 1 * 40000, SDS-PAGE Homo sapiens
3.4.11.3 monomer CAP-I, 1 * 61000, SDS-PAGE Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.3 6.8 8 CAP-II Homo sapiens
3.4.11.3 7.4 8 CAP-I Homo sapiens