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Literature summary extracted from

  • Hayashi, M.; Oshima, K.
    Purification and properties of oxytocinase (cystine amino-peptidase) from monkey placenta (1976), J. Biochem., 80, 389-396.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.11.3 Al3+
-
 Macaca fuscata fuscata
3.4.11.3 Ca2+ slightly Macaca fuscata fuscata
3.4.11.3 Cd2+
-
 Macaca fuscata fuscata
3.4.11.3 Co2+ at high concentration inhibition Macaca fuscata fuscata
3.4.11.3 EDTA
-
 Macaca fuscata fuscata
3.4.11.3 Hg2+
-
 Macaca fuscata fuscata
3.4.11.3 iodoacetic acid slightly Macaca fuscata fuscata
3.4.11.3 Mn2+ at high concentration inhibition; reverses EDTA inhibition Macaca fuscata fuscata
3.4.11.3 p-chloromercuribenzoate
-
 Macaca fuscata fuscata
3.4.11.3 Zn2+
-
 Macaca fuscata fuscata

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.11.3 additional information
-
 additional information
-
 Macaca fuscata fuscata

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.11.3 Ca2+ reversal of EDTA inhibition Macaca fuscata fuscata
3.4.11.3 Co2+ inhibition at high concentration Macaca fuscata fuscata
3.4.11.3 Mn2+ reversal of EDTA inhibition, inhibition at high concentration Macaca fuscata fuscata

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.11.3 87000
-
 gel filtration Macaca fuscata fuscata

Organism

EC Number Organism UniProt Comment Textmining
3.4.11.3 Macaca fuscata fuscata
-
 monkey
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.11.3
-
 Macaca fuscata fuscata

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.11.3 placenta
-
 Macaca fuscata fuscata
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.11.3 0.2087
-
-
 Macaca fuscata fuscata

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.11.3 oxytocin + H2O
-
 Macaca fuscata fuscata acyclic peptide + H2O
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.11.3 monomer 1 * 87000, SDS-PAGE Macaca fuscata fuscata

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.11.3 6.5
-
-
 Macaca fuscata fuscata