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Literature summary extracted from
- Microvillus membrane peptidases that catalyze hydrolysis of cysteinylglycine and its derivatives (1985), Methods Enzymol., 113, 471-484.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.2 | 1,10-phenanthroline | - |
Rattus norvegicus |  |
| 3.4.11.2 | bestatin | - |
Rattus norvegicus | |
| 3.4.11.2 | dithiothreitol | no significant inhibition by thiol compounds | Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.11.2 | membrane | brush border membrane | Rattus norvegicus | 16020 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.2 | Zn2+ | 2 mol Zn per mol enzyme | Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.2 | aminoacyl peptide | Rattus norvegicus | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.2 | Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.11.2 | side-chain modification | - |
Rattus norvegicus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.2 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.11.2 | kidney | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.2 | Ala-Gly | - |
Rattus norvegicus | Ala + Gly | - |
? | |
| 3.4.11.2 | Ala-Gly + H2O | - |
Rattus norvegicus | Ala + Gly | - |
? | |
| 3.4.11.2 | aminoacyl peptide | - |
Rattus norvegicus | ? | - |
? | |
| 3.4.11.2 | aminoacyl peptide + H2O | not glutathione | Rattus norvegicus | alanyl peptides + H2O | - |
? | |
| 3.4.11.2 | aminoacyl-p-nitroanilide + H2O | - |
Rattus norvegicus | amino acid + nitroaniline | - |
? | |
| 3.4.11.2 | dipeptides + H2O | not: D-Ala-Gly, Val-Gly, Asp-Gly, Gly-D-Ala, Pro-containing peptides | Rattus norvegicus | amino acids | - |
? | |
| 3.4.11.2 | tripeptides + H2O | - |
Rattus norvegicus | dipeptides + amino acids | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.2 | 7.5 | 8 | substrate Ala-Gly | Rattus norvegicus |
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Release 2023.1 (January 2023)
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