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Literature summary extracted from

  • Gething, M.J.; Davidson, B.E.; Dopheide, T.A.A.
    Chorismate mutase/prephenate dehydratase from Escherichia coli K12. 1. The effect of NaCl and its use in a new purification involving affinity chromatography on sepharosyl-phenylalanine (1976), Eur. J. Biochem., 71, 317-325.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.51 KCl
-
Escherichia coli
4.2.1.51 L-phenylalanine
-
Escherichia coli
4.2.1.51 NaCl
-
Escherichia coli
5.4.99.5 L-Phe
-
Escherichia coli
5.4.99.5 NaCl inhibition is cooperative, NaCl also increases the sensitivity of the enzyme to inhibition by Phe Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.51 prephenate Escherichia coli
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.51 Escherichia coli
-
-
-
5.4.99.5 Escherichia coli
-
K12
-
5.4.99.5 Escherichia coli
-
bifunctional enzyme chorismate mutase/prephenate dehydratase
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.51 bifunctional enzyme, chorismate mutase:prephenate dehydratase Escherichia coli
5.4.99.5 chorismate mutase/prephenate dehydratase Escherichia coli

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.51 32
-
-
Escherichia coli
5.4.99.5 52
-
-
Escherichia coli

Storage Stability

EC Number Storage Stability Organism
4.2.1.51 -20°C Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.51 prephenate
-
Escherichia coli phenylpyruvate + H2O + CO2
-
?
4.2.1.51 prephenate
-
Escherichia coli ?
-
?
5.4.99.5 Chorismate
-
Escherichia coli Prephenate
-
?