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Literature summary extracted from

  • Regoli, F.; Saccucci, F.; Principato, G.
    Mussel glyoxalase I as a possible marker for ecotoxicological studies: purification and preliminary characterization (1996), Comp. Biochem. Physiol. C, 113, 313-317.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.4.1.5 glutathione thioethers competitive Mytilus galloprovincialis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.4.1.5 0.8
-
 glutathione-methylglyoxal hemithioacetal
-
 Mytilus galloprovincialis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.4.1.5 additional information divalent cation required Mytilus galloprovincialis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.4.1.5 24000
-
 1 * 24000 + 1 * 25000, SDS-PAGE Mytilus galloprovincialis
4.4.1.5 25000
-
 1 * 24000 + 1 * 25000, SDS-PAGE Mytilus galloprovincialis
4.4.1.5 48000
-
 gel filtration Mytilus galloprovincialis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.5 additional information Mytilus galloprovincialis alpha-ketoaldehydes may be formed in cells during oxidative processes, glyoxalase I is the main enzyme involved in the detoxification pathway for these highly toxic compounds ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.5 Mytilus galloprovincialis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.4.1.5
-
 Mytilus galloprovincialis

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.4.1.5 digestive gland
-
 Mytilus galloprovincialis
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.4.1.5 83.2
-
-
 Mytilus galloprovincialis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.5 glutathione + methylglyoxal the substrat is the hemithioacetal of methylglyoxal and glutathione Mytilus galloprovincialis S-lactoylglutathione
-
 ?
4.4.1.5 glutathione-methylglyoxal hemithioacetal
-
 Mytilus galloprovincialis (R)-S-lactoylglutathione
-
 ?
4.4.1.5 additional information alpha-ketoaldehydes may be formed in cells during oxidative processes, glyoxalase I is the main enzyme involved in the detoxification pathway for these highly toxic compounds Mytilus galloprovincialis ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.4.1.5 dimer 1 * 24000 + 1 * 25000, SDS-PAGE Mytilus galloprovincialis