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Literature summary extracted from

  • Vancurova, I.; Vancura, A.; Volc, J.; Neuzil, J.; Behal, V.
    A further characterization of alanine dehydrogenase from Streptomyces aureofaciens (1989), J. Basic Microbiol., 29, 185-189.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.1.1 HgCl2
-
 Kitasatospora aureofaciens
1.4.1.1 L-Ala reductive amination of pyruvate Kitasatospora aureofaciens
1.4.1.1 L-Ser inhibition of aminating activity Kitasatospora aureofaciens
1.4.1.1 PCMB
-
 Kitasatospora aureofaciens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.1.1 198000
-
 analytical ultracentrifugation Kitasatospora aureofaciens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.4.1.1 L-Ala + H2O + NAD+ Kitasatospora aureofaciens physiological role in nitrogen metabolism in Streptomycetes pyruvate + NH3 + NADH
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.4.1.1 Kitasatospora aureofaciens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.1.1 L-Ala + H2O + 1,N6-etheno-NAD+ 45% of the activity with NAD+ Kitasatospora aureofaciens pyruvate + NH3 + 1,N6-etheno-NADH
-
 ?
1.4.1.1 L-Ala + H2O + 3-acetylpyridine-NAD+ as active as NAD+ Kitasatospora aureofaciens pyruvate + H2O + 3-acetylpyridine-NADH
-
 ?
1.4.1.1 L-Ala + H2O + 3-pyridinealdehyde-NAD+ 5.0% of the activity with NAD+ Kitasatospora aureofaciens ?
-
 ?
1.4.1.1 L-Ala + H2O + deamino-NAD+ 90.2% of the activity with NAD+ Kitasatospora aureofaciens pyruvate + NH3 + deamino-NADH
-
 ?
1.4.1.1 L-Ala + H2O + NAD+
-
 Kitasatospora aureofaciens pyruvate + NH3 + NADH
-
 r
1.4.1.1 L-Ala + H2O + NAD+ physiological role in nitrogen metabolism in Streptomycetes Kitasatospora aureofaciens pyruvate + NH3 + NADH
-
 ?
1.4.1.1 L-Ala + H2O + nicotinamide guanine dinucleotide 59.9% of the activity with NAD+ Kitasatospora aureofaciens ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.4.1.1 1,N6-etheno-NAD+ 45% of the activity with NAD+ Kitasatospora aureofaciens
1.4.1.1 3-acetylpyridine-NAD+ as active as NAD+ Kitasatospora aureofaciens
1.4.1.1 3-pyridinealdehyde-NAD+ 5.0% of the activity with NAD+ Kitasatospora aureofaciens
1.4.1.1 deamino-NAD+ 90.2% of the activity with NAD+ Kitasatospora aureofaciens
1.4.1.1 NAD+
-
 Kitasatospora aureofaciens
1.4.1.1 NADH
-
 Kitasatospora aureofaciens
1.4.1.1 nicotinamide guanine dinucleotide 59.9% of the activity with NAD+ Kitasatospora aureofaciens