EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.3 | 2-mercaptoethanol | 100 mM, full activation | Rattus norvegicus | |
1.2.1.3 | dithiothreitol | 4 mM, full activation | Rattus norvegicus | |
1.2.1.3 | GSH | 30% activation | Rattus norvegicus |
EC Number | General Stability | Organism |
---|---|---|
1.2.1.3 | freezing causes loss of activity | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.3 | benzaldehyde | substrate inhibition | Rattus norvegicus | |
1.2.1.3 | Butanal | substrate inhibition | Rattus norvegicus | |
1.2.1.3 | Ca2+ | 0.4 mM, 50% inhibition | Rattus norvegicus | |
1.2.1.3 | D-glyceraldehyde | substrate inhibition | Rattus norvegicus | |
1.2.1.3 | hexanal | substrate inhibition | Rattus norvegicus | |
1.2.1.3 | Isobutanal | substrate inhibition | Rattus norvegicus | |
1.2.1.3 | Mg2+ | 0.4 mM, 50% inhibition | Rattus norvegicus | |
1.2.1.3 | pentanal | substrate inhibition | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.1.3 | 0.004 | - |
hexanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.006 | - |
benzaldehyde | - |
Rattus norvegicus | |
1.2.1.3 | 0.006 | - |
pentanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.007 | - |
Butanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.023 | - |
propanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.03 | - |
Isobutanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.05 | - |
NAD+ | - |
Rattus norvegicus | |
1.2.1.3 | 0.246 | - |
acetaldehyde | - |
Rattus norvegicus | |
1.2.1.3 | 1.136 | - |
D-glyceraldehyde | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.3 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.2.1.3 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.2.1.3 | testis | - |
Rattus norvegicus | - |
EC Number | Storage Stability | Organism |
---|---|---|
1.2.1.3 | 4°C, phosphate buffer pH 7.4, containing 4 mM dithiothreitol or 10 mM 2-mercaptoethanol, stable for 8-10 days | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.3 | acetaldehyde + NAD+ + H2O | - |
Rattus norvegicus | acetate + NADH + H+ | - |
? | |
1.2.1.3 | benzaldehyde + NAD+ + H2O | - |
Rattus norvegicus | benzoate + NADH + H+ | - |
? | |
1.2.1.3 | butanal + NAD+ + H2O | - |
Rattus norvegicus | butyrate + NADH + H+ | - |
? | |
1.2.1.3 | D-glyceraldehyde + NAD+ + H2O | - |
Rattus norvegicus | D-glycerate + NADH + H+ | - |
r | |
1.2.1.3 | glyceraldehyde + NAD+ + H2O | - |
Rattus norvegicus | glycerate + NADH | - |
? | |
1.2.1.3 | hexanal + NAD+ + H2O | - |
Rattus norvegicus | hexanoate + NADH + H+ | - |
? | |
1.2.1.3 | isobutanal + NAD+ + H2O | - |
Rattus norvegicus | isobutyrate + NADH | - |
? | |
1.2.1.3 | pentanal + NAD+ + H2O | - |
Rattus norvegicus | pentanoate + NADH | - |
? | |
1.2.1.3 | propanal + NAD+ + H2O | - |
Rattus norvegicus | propionate + NADH | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 50 | - |
- |
Rattus norvegicus |
EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 45 | - |
90 min, pH 7.4, 0.2 M phosphate, 4 mM dithiothreitol, stable | Rattus norvegicus |
1.2.1.3 | 55 | - |
30 min, 20% loss of activity of diluted solution, 70% loss of activity of concentrated preparations | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 8.5 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
1.2.1.3 | 7.3 | 9.5 | 50% of maximal activity at pH 7.3 and at pH 9.5 | Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.3 | NAD+ | - |
Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.1.3 | 0.17 | - |
hexanal | - |
Rattus norvegicus | |
1.2.1.3 | 0.37 | - |
benzaldehyde | - |
Rattus norvegicus | |
1.2.1.3 | 0.54 | - |
pentanal | - |
Rattus norvegicus | |
1.2.1.3 | 4.35 | - |
Butanal | - |
Rattus norvegicus | |
1.2.1.3 | 14.32 | - |
D-glyceraldehyde | - |
Rattus norvegicus | |
1.2.1.3 | 100.1 | - |
Isobutanal | - |
Rattus norvegicus |