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Literature summary extracted from

  • Russwurm, M.; Behrends, S.; Harteneck, C.; Koesling, D.
    Functional properties of a naturally occurring isoform of soluble guanylyl cyclase (1998), Biochem. J., 335, 125-130.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.2 CO activation Homo sapiens
4.6.1.2 NO activation Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.6.1.2 expression of isoform alpha2,beta1 in Sf9 cells Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.6.1.2 0.09
-
 GTP
-
 Homo sapiens
4.6.1.2 0.1
-
 GTP alpha2,beta1 isoform Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.2 soluble
-
 Homo sapiens
-
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.6.1.2 70000
-
 alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form Homo sapiens
4.6.1.2 73000
-
 alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.2 Homo sapiens P33402
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.2 placenta
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.2 GTP GTP in form of MgGTP2- Homo sapiens 3',5'-cyclic GMP + diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.6.1.2 dimer alpha,beta 1 * 73000 + 1 * 70000, SDS-PAGE, soluble form Homo sapiens