Literature summary extracted from

Dolphin, C.T.; Janmohamed, A.; Smith, R.L.; Shephard, E.A.; Phillips, I.R.
Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FMO3) gene in patients with fish-odour syndrome (2000), Pharmacogenetics, 10, 799-807.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.14.13.8	missense mutations causing fish-odour syndrome	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.13.8	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.13.8	liver	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.13.8	methimazole + NADPH + O2	FMO3 5000 times more efficient than FMO5	Homo sapiens	N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O	-	?
1.14.13.8	trimethylamine + NADPH + O2	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)