Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Poulsen, L.L.; Hyslop, R.M.; Ziegler, D.M.
    S-Oxygenation of N-substituted thioureas catalyzed by the pig liver microsomal FAD-containing monooxygenase (1979), Arch. Biochem. Biophys., 198, 78-88.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.14.13.8 n-octylamine
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.13.8 additional information
-
 additional information 2 Km values for oxygenation of thiocarbamides: 1. Km1 for oxygenation to sulfenic acid, 2. Km2 for oxygenation of sulfenic acid to sulfinic acid Sus scrofa
1.14.13.8 additional information
-
 additional information 2 Km values for oxygenation of thiocarbamides: 1. Km1 for oxygenation to sulfenic acid, 2. Km2 for oxygenation of sulfenic acid to sulfinic acid Mesocricetus auratus

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.8 Mesocricetus auratus
-
-
-
1.14.13.8 Sus scrofa
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.14.13.8 N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O reaction mechanism of S-oxygenation of N-substituted thioureas Sus scrofa
a
1.14.13.8 N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O reaction mechanism of S-oxygenation of N-substituted thioureas Mesocricetus auratus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.8 liver
-
 Sus scrofa
-
1.14.13.8 liver
-
 Mesocricetus auratus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.8 2-mercaptobenzimidazole + NADPH + O2
-
 Sus scrofa ?
-
 ?
1.14.13.8 ethylenthiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?
1.14.13.8 methimazole + NADPH + O2
-
 Sus scrofa N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O
-
 ?
1.14.13.8 additional information S-oxygenation of N-substituted thioureas Sus scrofa ?
-
 ?
1.14.13.8 additional information S-oxygenation of N-substituted thioureas Mesocricetus auratus ?
-
 ?
1.14.13.8 N,N-dimethylaniline + NADPH + O2
-
 Sus scrofa N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 N,N-dimethylaniline + NADPH + O2
-
 Mesocricetus auratus N,N-dimethylaniline N-oxide + NADP+ + H2O
-
 ?
1.14.13.8 phenylthiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?
1.14.13.8 thiocarbanilide + NADPH + O2
-
 Sus scrofa ?
-
 ?
1.14.13.8 thiourea + NADPH + O2
-
 Sus scrofa ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.8 FAD flavoprotein Sus scrofa
1.14.13.8 FAD flavoprotein Mesocricetus auratus